Thoracic surgery

Reduce the incidence of prolonged air leaks

Thoracic surgery

One of the most common complications in thoracic surgery is prolonged air leakage. Vivostat® Fibrin has been shown to reduce the incidence of prolonged air leaks and thereby enabling faster drain removal.

Vivostat® Fibrin is not only an excellent sealant, some of the main features that makes the product an optimal solution in this special surgical field is the outstanding properties for elasticity and polymerization that are out most important for a positive outcome:

Elasticity: the sealant must be very elastic, so it is possible to apply the product on a deflated lung without compromising physical properties when the lung is re-inflated. Most compounds have an inverse relationship between strength and elasticity. However, comparative tests have shown, that Vivostat® Fibrin is more than three times as flexible as conventional products while maintaining sufficient strength.

Polymerisation: the sealant must have a fast polymerisation that ensure the sealant remains where applied. The polymerisation is activated by a pH change and it polymerise immediately on application, which is why it stays where applied – even in wet environment and inverted surfaces. The polymerisation rates for Vivostat® Fibrin are much faster than with conventional sealants.
Thoracic surgeons find Vivostat® Fibrin most useful for the following surgical procedures:

  • Lobectomy
  • Long volume reduction surgery
  • Wedge resections
  • Bullectomy
  • Spontaneous pneumothorax
  • Pulmonary resections

The Vivostat® Fibrin have an endoscopic solution suitable for all VATS (video-assisted thoracic surgery) and robotic procedures.

For bronchopleural fistula (BPF) closure many chooses to use Vivostat® PRF due to the regenerative qualities the product holds.

main advantages using vivostat®


With the Vivostat® System you can always find and choose the optimal application device for the specific surgical application. All our applications devices hold the unique feature of intermittently use without experiencing total blockage. At same time, they all deliver the product to the surgical site in a precise and targeted manner.

The endoscopic solutions that can also be used for robotic procedures or the Vivostat® Spraypen is often used in thoracic surgery. The pre-bent nozzle can easily be pointed in multiple directions, giving the surgeon full freedom and control of the application.


Vivostat® in thoracic surgery

Click on the video and see the Vivostat® System in use in thoracic surgery.

Application devices

The Vivostat® System offers a variety of different disposable application devic­es as well as a number of reusable handles.

Vivostat® Fibrin

Our autologous fibrin show best-in-market results on parameters such as time to haemostasis, elasticity, adhesion to and impact on tissue. 

Belboul, A., Dernevik, L., Aljassim, O., Skrbic, B., Rådberg, G., & Roberts, D. (2004), The effect of autologous fibrin sealant (Vivostat) on morbidity after pulmonary Lobectomi – a prospective randomized, blinded study, European Journal of Cardiothoracic Surgery, 26(6), 1187–1191,

Moser, C., Opitz, I., Zhai, W., Rousson, V., Russi, E. W., Weder, W., & Lardinois, D. (2008), Autologous fibrin sealant reduces the incidence of prolonged air leak and duration of chest tube drainage after lung volume reduction surgery: A prospective randomized blinded study, The Journal of Thoracic and Cardiovascular Surgery, 136(4), 843–849,

Belcher, E., Dusmet, M., Jordan, S., Ladas, G., Lim, E., & Goldstraw, P.  (2010), A prospective, randomized trial comparing BioGlue and Vivostat for the control of alveolar air leak, The Journal of Thoracic and Cardiovascular Surgery, 140(1), 32–38,

Jacobs, J., Welter, S., Altmayer, M., Breull, A., & Stamatis, G. (2010). Autologer Fibrinkleber in der Thoraxchirurgie: Machbarkeitsstudie in einem Zentrum. Presented at the Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizer Gesellschaft für Thoraxchirurgie, Wien, Österreich.

Kılıç, B., Erşen, E., Demirkaya, A., Kara, H. V., Alizade, N., İşcan, M. Y., Kaynak, K., & Turna, A. (2017), A prospective randomized trial comparing homologous and autologous fibrin sealants for the control of alveolar air leak, Journal of Thoracic Disease, 9(9), 2915-2922,

Jacobs, J. (n.d.). Autologous Fibrin sealant (Vivostat) in General Surgery Post interventional survey at three exemplary patients. Department of Thoracic Surgery and Thoracic Endoscopy; Essen, Germany.