Neurosurgery
OPTIMAL SEALING AND LOW IMPACT ON TISSUE
Neurosurgery
The Vivostat® System is used in neurosurgery globally. The uniqueness of the application devices combined with the sealant/matrix physical properties makes it a match for surgeries related to the brain and nerves.
The Vivostat® application devices come with the possibility to control the delivery of the product including a “No Air” mode, which have very low impact on the tissue and vital organs/nerves in the skull. Combined with the extreme accuracy and precision spraying this mode is perfect for neurosurgery.
Neurosurgeons most often use the Vivostat® Fibrin or Vivostat® PRF for:
- Open cranium procedures
- Transsphenoidal (transnasal) surgery’
- Dural closure/CSF leakages
- Dural defects repair
- Spine reconstructions
- Chiari
- Nerve anastomoses
One of the main challenges in neurosurgery is cerebrospinal fluid (CSF) leakage. Autologous Vivostat® Fibrin and Vivostat® PRF products are optimal solutions for reduction of CSF leaks. Managing CSF leakages pro-actively can help reduce complications and contain the total cost of the treatment.
In transsphenoidal procedures Vivostat® PRF is used for sealing the dura, sealing and regeneration of sphenoidal bone and cover the sinus area, lowering post-op bleedings and infections.
main advantages using vivostat®
- Reduce risk of CSF leakages
- Low impact on tissue and vital organs/nerves
- Filler in “dead spaces”
- Sealing and regeneration of dura and sphenoidal bone
Vivostat® Fibrin: autologous fibrin outperforming other fibrin sealants in key parameters such as polymerization, elasticity, adhesion, and its impact on tissue.
Vivostat® PRF: cutting-edge autologous platelet rich fibrin matrix, functioning as both a haemostat/sealant and a supportive agent for tissue repair.
Vivostat® in neurosurgery
Click on the video and see the Vivostat® System in use in neurosurgery.
Vivostat® Fibrin
Our autologous fibrin show best-in-market results on parameters such as time to haemostasis, elasticity, adhesion to and impact on tissue.
Vivostat® PRF
Using the Vivostat® System, you can prepare autologous platelets with multiple growth factors embedded in a matrix.
Poulsgaard, L., Mørck, A., & Holm, N. (2007). A safety study of the use of VivoStat® Patient-Derived fibrin sealant containing tranexamic acid in neurosurgery. Skull Base, 17(S 2). https://doi.org/10.1055/s-2007-981728
Bovenzi, D., et al. (2007). Use of autologous fibrin adhesive in neurosurgery. Presented at SIDEM (Società Italiano di Emaferesi e Manipollazione Cellulare).
Yıldırım, A. E., Dursun, E., Özdöl, Ç., Divanlıoğlu, D., Nacar, O. A., Koyun, O. K., Ilmaz, A. E., & Belen, A. D. (2013). Using an autologous fibrin sealant in the preventing of cerebrospinal fluid leak with large skull base defect following endoscopic endonasal transsphenoidal surgery. Turkish Neurosurgery. https://doi.org/10.5137/1019-5149.jtn.7750-12.0
Tomazic, P. V., Edlinger, S., Gellner, V., Koele, W., Gerstenberger, C., Braun, H., Mokry, M., & Stammberger, H. R. (2014). Vivostat®: an autologous fibrin sealant as useful adjunct in endoscopic transnasal CSF-leak repair. European Archives of Oto-Rhino-Laryngology, 272(6), 1423–1427. https://doi.org/10.1007/s00405-014-3230-0
Graziano, F., Certo, F., Basile, L., Maugeri, R., Grasso, G., Meccio, F., Ganau, M., & Iacopino, D. G. (2015), Autologous fibrin sealant (Vivostat) in the neurosurgical practice: Part I: Intracranial surgical procedure, Surgical Neurology International, 6(1), 77, https://doi.org/10.4103/2152-7806.156871
Graziano, F., Maugeri, R., Basile, L., Meccio, F., & Iacopino, D. G. (2016), Aulogous fibrin sealant (Vivostat) in the neurosurgical practice: Part II: Vertebro-spinal procedures, Surgical Neurology International, 7(4), 77, https://doi.org/10.4103/2152-7806.174894
Baptista, P. M., Fernández, S., Bejarano, B., & Manrique, R. (n.d.). Use of fibrin sealant (Vivostat®) in skull base surgery.
