Neurosurgery

OPTIMAL SEALING AND LOW IMPACT ON TISSUE

Neurosurgery

The Vivostat® System is used in neurosurgery globally. The uniqueness of the application devices combined with the sealant/matrix physical properties makes it a match for surgeries related to the brain and nerves.

The Vivostat® application devices come with the possibility to control the delivery of the product including a “No Air” mode, which have very low impact on the tissue and vital organs/nerves in the skull. Combined with the extreme accuracy and precision spraying this mode is perfect for neurosurgery.

Neurosurgeons most often use the Vivostat® Fibrin or Vivostat® PRF for:

  • Open cranium procedures
  • Transsphenoidal (transnasal) surgery’
  • Dural closure/CSF leakages
  • Dural defects repair
  • Spine reconstructions
  • Chiari
  • Nerve anastomoses

One of the main challenges in neurosurgery is cerebrospinal fluid (CSF) leakage. Autologous Vivostat® Fibrin and Vivostat® PRF products are optimal solutions for reduction of CSF leaks. Managing CSF leakages pro-actively can help reduce complications and contain the total cost of the treatment.

In transsphenoidal procedures Vivostat® PRF is used for sealing the dura, sealing and regeneration of sphenoidal bone and cover the sinus area, lowering post-op bleedings and infections.

main advantages using vivostat®

Vivostat® Fibrin: autologous fibrin outperforming other fibrin sealants in key parameters such as polymerization, elasticity, adhesion, and its impact on tissue.

Vivostat® PRF: cutting-edge autologous platelet rich fibrin matrix, functioning as both a haemostat/sealant and a supportive agent for tissue repair.

Play Video

Vivostat® in neurosurgery

Click on the video and see Vivostat® Fibrin used in preventing CSF leaks. We have also gathered a showcase of  Vivostat® used during neurosurgery.

Vivostat® Fibrin

Our autologous fibrin show best-in-market results on parameters such as time to haemostasis, elasticity, adhesion to and impact on tissue. 

Vivostat® PRF

Using the Vivostat® System, you can prepare autologous platelets with multiple growth factors embedded in a matrix. 

Poulsgaard, L., Mørck, A., & Holm, N. (2007). A safety study of the use of VivoStat® Patient-Derived fibrin sealant containing tranexamic acid in neurosurgery. Skull Base, 17(S 2). https://doi.org/10.1055/s-2007-981728

Bovenzi, D., et al. (2007). Use of autologous fibrin adhesive in neurosurgery. Presented at SIDEM (Società Italiano di Emaferesi e Manipollazione Cellulare).

Yıldırım, A. E., Dursun, E., Özdöl, Ç., Divanlıoğlu, D., Nacar, O. A., Koyun, O. K., Ilmaz, A. E., & Belen, A. D. (2013). Using an autologous fibrin sealant in the preventing of cerebrospinal fluid leak with large skull base defect following endoscopic endonasal transsphenoidal surgery. Turkish Neurosurgery. https://doi.org/10.5137/1019-5149.jtn.7750-12.0

Tomazic, P. V., Edlinger, S., Gellner, V., Koele, W., Gerstenberger, C., Braun, H., Mokry, M., & Stammberger, H. R. (2014). Vivostat®: an autologous fibrin sealant as useful adjunct in endoscopic transnasal CSF-leak repair. European Archives of Oto-Rhino-Laryngology, 272(6), 1423–1427. https://doi.org/10.1007/s00405-014-3230-0

Graziano, F., Certo, F., Basile, L., Maugeri, R., Grasso, G., Meccio, F., Ganau, M., & Iacopino, D. G. (2015), Autologous fibrin sealant (Vivostat) in the neurosurgical practice: Part I: Intracranial surgical procedure, Surgical Neurology International, 6(1), 77, https://doi.org/10.4103/2152-7806.156871

Graziano, F., Maugeri, R., Basile, L., Meccio, F., & Iacopino, D. G. (2016), Aulogous fibrin sealant (Vivostat) in the neurosurgical practice: Part II: Vertebro-spinal procedures, Surgical Neurology International, 7(4), 77, https://doi.org/10.4103/2152-7806.174894

Baptista, P. M., Fernández, S., Bejarano, B., & Manrique, R. (n.d.). Use of fibrin sealant (Vivostat®) in skull base surgery.