Orthopaedic surgery
IMPROVE PATIENT OUTCOMES THROUGH FAST RECOVERY
Orthopaedic surgery
Vivostat® offer the ArthroZheal® solution specifically designed to improve patient outcomes through fast recovery. ArthroZheal® is an autologous, biocompatible and bioactive matrix improving regeneration of ligaments, tendons, menisci and cartilage.
The Vivostat® System has been used in orthopaedic surgery for decades and with our newest product, ArthroZheal®, we have an even better targeted solution for arthroscopic surgery. The list of indications where ArthroZheal® successfully has been used includes:
- Arthroscopy – sports medicine:
- Knee – meniscal repairs, anterior cruciate ligaments (ACL)
- Knee – chondral lesions
- Hip – femoroacetabular impingement (FAI)
- Shoulder – rotator cuff
- Ankle – chondral lesions
- Joint replacements
- Knee
- Hip
- Revision procedures
- Infiltrations in joints, tendons and ligaments
- Orthopaedics wound management
Frequent challenges in orthopaedic and sports medicine are regeneration of tissue and bleeding. The Vivostat® System addresses these challenges not only by minimizing bleeding but also by stimulating the regeneration of damaged tissue (tendons, ligaments and muscles).
Successfully handling challenges can have a positive effect on complications and reoperations, leading to faster rehabilitation, lower pain, shorter hospital stays and lower overall procedure costs.
main advantages using vivostat®
- Sealant and hemostat – less hemarthrosis
- Regenerative product – graft maturation, osteoinduction
- Acts as a scaffold – membrane
- Platform for antibiotics applications
- Platform for stem cell applications
KEY WHEN IT COMES TO INFECTION CONCERNS
A major concern in orthopaedic and sports medicine is infections. Research within the area shows that platelets in itself have an antibacterial effect, however the Vivostat® System also makes it possible to co-apply antibiotics directly at the surgical site together with the matrix. Furthermore, the applied substance (not limited to antibiotics, but could also be other medications, BMAC, stem cells or chondrocytes) gets mixed with the matrix, which allow the substance to be released over time providing a sustained local release.
Play Video
Vivostat® in orthopaedic surgery
Click on the video and see Vivostat® used during cartilage repair. In our showcase you can see our products used in a wide range of orthopaedic surgeries.
Vivostat® Co-Delivery
The revolutionary system makes it possible to co-apply e.g. stem cells or antibiotics with the Vivostat® product.
ArthroZheal®
Successfully provides supportive effects for sealing, healing and regeneration of ligaments, tendons and cartilage.
- Pillai, A. (2025), A novel surgical revision with custom implant and local prophylactic antibiotic delivery regime following failed 2-stage ankle fusion with osteomyelitis (to get a copy of the case study, contact your distributor)
- Tai, K. M., Mooteeram, J., & Pillai, A. (2025). The use of Platelet-Rich Fibrin-Coated Three-Dimensionally (3D) printed scaffolds in salvage of complex hindfoot cases. Biomimetics, 10(5), 269. https://doi.org/10.3390/biomimetics10050269
- Skarpas, G. A., Maniastis, K., Barmpounakis, N., & Kakavas, G. (2024), Meniscal repair with ArthroZheal an autologous bioactive fibrin scaffold. A new technique and treatment option, Surgical Technology International, 44, 1783, https://doi.org/10.52198/24.sti.44.os1783
- Pillai, A. (2024), A novel local antibiotic delivery/prophylaxis system with PRF matrix for total talus replacement in avascular necrosis of the talus (to get a copy of the case study, contact your distributor)
- Milovanović, D., Vukman, P., Gavrilović, D., Begović, N., Stijak, L., Srećković, S., & Kadija, M. (2024), The influence of platelet-rich fibrin on the healing of bone defects after harvesting bone–patellar tendon–bone grafts, Medicina Kaunas, Lithuania, 60(1), 154, https://doi.org/10.3390/medicina60010154
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- Tandoğan, R. N., Polat, M., Beyzadeoğlu, T., Karabulut, E., Yıldırım, K., & Kayaalp, A. (2021), Topical co-delivery of platelet rich fibrin and tranexamic acid does not decrease blood loss in primary total knee arthroplasty compared to the standard of care: a prospective, randomized, controlled trial, Knee Surgery, Sports Traumatology, Arthroscopy official journal of the ESSKA, 29(2), 519–528, https://doi.org/10.1007/s00167-020-05938-1
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- Beyzadeoğlu, T., Pehlivanoğlu, T., Yıldırım, K., Buldu, H., Tandoğan, R. N., & Tüzün, Ü. (2020), Does the application of platelet-rich fibrin in anterior cruciate ligament reconstruction enhance graft healing and maturation? A comparative MRI study of 44 cases, Orthopaedic Journal Sports Medicine, 8(2), 232596712090201, https://doi.org/10.1177/2325967120902013
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- Dallari, D., Rani, N., Sabbioni, G., Mazzotta, A., Cenacchi, A., & Savarino, L. (2016), Radiological assessment of the PRF/BMSC efficacy in the treatment of aseptic nonunions: A retrospective study on 90 subjects, Injury, 47(11), 2544–2550, https://doi.org/10.1016/j.injury.2016.09.021
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- Vadalà, G., Di Martino, A., Tirindelli, M. C., Denaro, L., & Denaro, V. (2008), Use of autologous bone marrow cells concentrate enriched with platelet-rich fibrin on corticocancellous bone allograft for posterolateral multilevel cervical fusion, Journal of tissue engineering and regenerative medicine, 2(8), 515–520, https://doi.org/10.1002/term.121
