Fibroblasts are fundamentally important in the process of tissue repair.

Apart from producing structural proteins such as collagen, they stimulate both angiogenesis and epithelialisation.

In-vitro studies have proven the positive effect of Vivostat PRF® on fibroblast proliferation. As illustrated, Vivostat PRF® increases the growth of normal human skin fibroblasts compared to control and performs significantly better than PDGF-BB (commercial growth factor).

Bioactivity and stability of endogenous fibrogenic factors in platelet-rich fibrin, Lundquist R. et al., Wound Repair and Regeneration 2008; 16(3): 356-63